We believe innovation and technology are key to advancing healthcare, improving outcomes, and advancing pain medicine.
Join us in finding novel and creative ways to advance our mission by taking part in our Innovation Challenge, designed specifically for innovators, healthcare entrepreneurs, startups, researchers, and teams with solutions to improve the lives of people living with pain across all specialties and fields of medicine.

About the Innovation Challenge
The Innovation Challenge is an open invitation to innovators worldwide, from pre-seed to Series A companies, to present their groundbreaking solutions across various fields, including pain management, nutrition, sleep medicine, and more.
Every year, the “Shark Tank” style pitch competition pits established startups, aspiring healthcare entrepreneurs, and researchers against one another with the ultimate goal of improving the lives of people living with pain.
Presented by the American Academy of Pain Medicine (AAPM), combined with the resources and support of the world’s most prestigious healthcare innovation group, MIT Hacking Medicine, the Innovation Challenge is one of the most exciting annual events in the pain medicine space.
Finalists will pitch their solution before an audience of patients, providers, and industry leaders, offering prizes, mentorship, and exposure to propel innovations forward.
Ready to Join the Innovation Challenge?
Our Mission
We want to create an innovation ecosystem capable of catalyzing lasting change in pain management and making a tangible difference in the lives of those affected by pain. The Innovation Challenge is an important component of our mission.
Join us in this journey of discovery and innovation, where your ideas can lead to transformative solutions in pain medicine.
2026 Finalists

EX-Neuro
Project Title: Nerve-NET Closed Loop Peripheral Nerve Stimulation
Team: Bryan McLaughlin, PhD, Matt Pingree, MD, Amit Gulati, MD, Chad Andresen, MS, Ilknur Telkes, PhD

FaraMed Tech
Project Title: A non-invasive wearable neuromodulation system.
FaraMed Tech is an Innovation Challenge Finalist invited back to pitch an update for the Innovation Challenge’s 5th Anniversary.
Team: James S. Khan, MD, MSc, FRCPC, Vivek Saini BASc
2025 Finalists

Lutroo Imaging
Project Title: RadiocaineTM: faster, cheaper, accurate diagnosis
Lutroo Imaging is an Innovation Challenge Finalist invited back to pitch an update for the Innovation Challenge’s 5th Anniversary.
Team: Braxton Norwood, PhD, Anthony Babb, RN, MS

Nalu Bio
Project: Unlocking the Endocannabinoid System (ECS) to advance AI-powered, non-addictive drug development for acute and chronic pain.
Team: Caitlyn Krebs, Grazia Piizzi, PhD, Tom Perterson, PhD, Alex Dorenbaum, MD, Glenn Sammis, PhD, Chief Chemist

Wellness Wits
Project: Group Therapeutics: Transformative Healthcare Through Community Power
Wellness Wits is an Innovation Challenge Finalist invited back to pitch an update for the Innovation Challenge’s 5th Anniversary.
Team: KiKe Oduba, MD, MPH

Xaia
Project: Xaia: Clinical AI for Specialty Care
Team: Gabe Zetter, Omer Liran, MD
Join Us for the Next Innovation Challenge
This year’s competition will be held at the Grand American Hotel in Salt Lake City, UT, on March 7, 2026.
These six visionary teams will pitch their innovations live at PainConnect 2026, where they will compete for funding, mentorship, and the chance to revolutionize pain treatment.
Be there for this high-energy, Shark Tank-style competition and get a front-row seat to the future of pain management. Don’t miss your chance to connect with thought leaders, industry pioneers, and the next generation of innovators!
Who are the Judges?
Judges will meet with winning teams to provide mentorship and support in furthering their idea.
2026 Judges including:
- Bunny Ellerin, CEO & Founder, Digital Health New York
- Sean Day, Venture Principal, Rock Health
- Zachary L. McCormick, MD, Chief of Spine and Musculoskeletal Medicine, University of Utah
- Pierre Mourad, PhD, Program Manager, Scalable Solutions, ARPA-H
- Casey Cashman, Director of Pediatric Pain Warrior, U.S. Pain Foundation
- M. Christine Stock, MD, Managing Director, Medical Affairs, Health2047
Judging Criteria
Potential for Impact (25%)
- Each submission will be rated on the strength of its potential to improve the health of individuals and/or communities specific to pain medicine diagnosis defined above.
- Applications will be rated on their ability to address a specific need and potential for further development.
Design and Usability (25%)
- Each submission will be rated on how well it meets the specific needs of its intended user.
- User-friendliness and human-centered design.
- Priority may be given to submissions that are easily accessible to a range of patients and on a variety of platforms.
Solution Feasibility (25%)
- Solution will be rated on the presented market analysis and proposed plan for development, growth, scale, and sustainability.
Creativity and Innovation (25%)
- Each submission will be rated for the degree of creativity and innovation compared with existing solutions.

The Prizes
- 1 Grand Prize – Subhash Jain Award
- 1 Runner-up Prize – MM Sadipe Entrepreneurship Award $1,000
- Sponsor Award – selected and presented solely by one major sponsor

Subhash Jain Award
MM Sadipe Award

Frequently Asked Questions
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